Job Details

  • Reference number: E240106
  • Type of engagement:
  • Posted: February 6th
  • Remuneration package: The annual cost of employment for 2023, including benefits, is between R711 889 and R837 514.

Background to Position

Project Manager

(Payclass 11; 4½ years contract)

Clinical Research Centre

Faculty of Health Sciences

The Clinical Research Centre (CRC) invites applications from suitably qualified candidates to fill a Project Manager post on a 4½ -year full-time contract. The incumbent will be based at the CRC offices at the Old Main Building at Groote Schuur Hospital but will attend other sites as required. 

The main purpose of this position is overseeing and supporting the study sites with a view to improving effectiveness, efficiency and forward planning across the various sites of a large multi-centre trial in Africa. The CRC aims to support its staff in their conduct of high-quality clinical research through advice, services and facilities. We are seeking an experienced, dynamic individual to work with investigators and their teams in their conduct of their clinical trials at various sites across Africa. You will work with a friendly and dynamic team in a Centre of Excellence in trials.

Job Description


• Managing clinical research activities across multiple sites, including but not limited to coordinating:

1) Regulatory and ethics applications and renewals

2) Study contracts negotiation and set up (with sites and vendors)

3) Writing and review of standard operating procedures (SOPs) and training materials

4)  Start-up procedures (arrange training, site initiation visits, etc.)

5) On-boarding new sites and site staff

6) Recruitment and retention of participants across sites

7) Data management across sites (oversight)

8) Study close-out activities and archiving

• Serve on the Project Management Team (PMT) and attend meetings of the PMT to contribute to (including but not limited to):

1) Supporting site institutional review boards (IRB) and regulatory approvals

2) Monitoring and providing support for recruitment and follow up for all sites

3) Logistics for remote and in-person SC meetings

4) Data management including QA/QC

• Organise, chair, and keep records for project team meetings

• Oversight of UCT project team activities, including purchasing, finance, human resources, site monitoring, data quality, training

• Coordinate and organise training exchange visits between sponsor and UCT

• Coach, mentor, motivate, influence, and supervise team members to take positive action and accountability for their assigned work

• Ensure that staff are developed to their full potential by identifying training needs and coordinating training and development.

Inherent Criteria


  • University degree in a health or social science subject
  • Minimum 5 years’ experience coordinating or managing multi-centre clinical trials
  • Database management skills
  • Financial management and procurement for research studies
  • Clinical trial coordination, monitoring, and good clinical practice
  • GCP certification
  • In-depth knowledge of regulations and implementation of clinical trials
  • Excellent communication skills
  • Excellent organisational and administrative skills
  • Attention to detail
  • Ability to work in a team environment
  • Ability to take initiative.
  • Ability to coordinate multiple aspects of a project.
  • Ability to travel to trial sites and investigator meetings.


  • Master’s in Public Health or similar postgraduate qualification 
  • Formal training in trial coordination, monitoring and/or project management
  • Experience managing multi-site studies in Africa

Application Requirement

To apply, please e-mail the below documents in a single pdf file to Ms Tracy Moore at

- UCT Application Form (download at

- Letter of motivation that speaks to the specific requirements of the position

- Curriculum vitae (CV)

- Copy of South African Good Clinical Practice (GCP) certification

Please ensure the title and reference number are indicated in the subject line.

An application which does not comply with the above requirements will be regarded as incomplete. 

Only shortlisted candidates will be contacted and may be required to undergo an assessment.

Telephone: 021 650 5405 Website:

Reference number: E240106 Closing date: 15 February 2024

UCT is a designated employer and is committed to the pursuit of excellence, diversity and redress in achieving its equity targets in accordance with the Employment Equity Plan of the University and its Employment Equity goals and targets. Preference will be given to candidates from the under-represented designated groups.Our Employment Equity Policy is available at policies/eepolicy.pdf.  

UCT reserves the right not to appoint.

About University of Cape Town

The University of Cape Town (UCT) is South Africa's oldest university, and is one of Africa's leading teaching and research institutions. UCT was founded in 1829 as the South African College, a high school for boys. The College had a small tertiary-education facility that grew substantially after 1880, when the discovery of gold and diamonds in the north – and the resulting demand for skills in mining – gave it the financial boost it needed to grow. The College developed into a fully fledged university during the period 1880 to 1900, thanks to increased funding from private sources and the government.