Job Details

  • Reference number: TGB02/070/0324
  • Province: Western Cape
  • Type of engagement: Permanent appointment
  • Posted: April 12th

Background to Position

Stellenbosch University

Department of Biomedical Sciences

Molecular Biology and Human Genetics Division

Research Assistant in the TB Genomics Group (Job Level 11)

(Two-year fixed-term contract with the possibility of renewal)

Ref. TGB02/070/0324

Kindly note that priority will be given to South African citizens who meet the requirements as set out below.

We are seeking a research assistant in the TB Genomics Group in the Division of Molecular Biology and Human Genetics at Stellenbosch University (SU). The incumbent will have the opportunity to work with a dynamic, multidisciplinary group of researchers that are part of the SAMRC Centre for TB Research. This Postdoctoral Fellow Award is funded by the NIH research project entitled “An RNA nano sensor for the diagnosis of antibiotic resistance in M. tuberculosis”. The research assistant will work on the identification of Mycobacterium tuberculosis RNA signatures in response to antibiotic treatment. These signatures will be used to inform the development of diagnostics to rapidly determine whether clinical isolates of Mycobacterium tuberculosis are susceptible to a particular anti-TB drug. 

Job Description


  • Culture of Mycobacterium tuberculosis;
  • RNA extraction;
  • cDNA synthesis; 
  • RT-qPCR;
  • Illumina library preparation;
  • High throughput sequencing;
  • SOP development.

Inherent Criteria


  • MSc degree in microbiology, or biochemistry, or molecular biology, or mycobacteriology, or bioinformatics;
  • A track record in undertaking research;
  • Strong written and verbal communication skills.


  • Experience in the field of Tuberculosis (working under BSL-3 conditions); 
  • Experience in next generation sequencing methods and subsequent bioinformatics analyses (RNA- seq will be preferred);
  • Experience in molecular biology methods (experience with RNA manipulation will be advantageous).

Application Requirement

Enquiries regarding this post: Prof RM Warren on 021 938 9251, or at

Enquiries regarding remuneration/benefits, as well as technical assistance with the electronic application process: Human Resources Client Services Centre on 021 808 2753, or at

Commencement of duties:

01 June 2024

Closing date:

25 April 2024

Stellenbosch University is committed to employment equity (EE). In accordance with the institutional EE plan of the University and the EE Plan of the specific environment, persons from designated groups will receive preference over foreign nationals where EE targets are a factor. Where EE is not a factor, South African citizens will receive preference over foreign nationals.

Stellenbosch University reserves the right not to make an appointment.


Your application, comprising a comprehensive curriculum vitae (including the names and email addresses of at least three referees), must reach the University before or on the closing date of the advertised post. 

The University reserves the right to investigate qualifications and conduct background checks on all candidates.

The Occupational Health and Safety Act requires people in occupations that entail potential exposure to certain hazards (such as, but not limited to: noise, hazardous chemical substances and hazardous biological agents) to be subjected to medical screening, to determine their fitness to work in the said occupations.

Should no feedback be received from the University within four to six weeks of the closing date, kindly accept that your application did not succeed.

About Stellenbosch University

Stellenbosch University (SU) is home to an academic community of 29 000 students (including 4 000 foreign students from 100 countries) as well as 3 000 permanent staff members (including 1 000 academics) on five campuses. ​The historical oak-lined university town amongst the Boland Mountains in the winelands of the Western Cape creates a unique campus atmosphere, which attracts local and foreign students alike. On the main campus, paved walkways wind between campus buildings – some dating from previous centuries; others just a few years old. Architecture from various eras attests to the sound academic foundation and establishment of an institution of excellence. This, together with the scenic beauty of the area; state-of-the-art, environmentally friendly facilities and technology, as well as visionary thinking about the creation of a sustainable 21st-century institution, makes for the unique character of Stellenbosch University.